Phospho-Insulin Receptor beta-Y1189 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-Insulin Receptor beta-Y1189 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Type I insulin-like growth factor receptor (IGF-IR) is a transmembrane receptor tyrosine kinase that is widely expressed in many cell lines and cell types within fetal and postnatal tissues (1-3). Receptor autophosphorylation follows binding of the IGF-I and IGF-II ligands. Three tyrosine residues within the kinase domain (Tyr1131, Tyr1135, and Tyr1136) are the earliest major autophosphorylation sites (4). Phosphorylation of these three tyrosine residues is necessary for kinase activation (5,6). Insulin receptors (IRs) share significant structural and functional similarity with IGF-I receptors, including the presence of an equivalent tyrosine cluster (Tyr1146/1150/1151) within the kinase domain activation loop. Tyrosine autophosphorylation |
| Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y1189 of human Insulin Receptor beta |
| Other Names | [Phospho-INSR-Y1189: INSR; HHF5; CD220], [INSR; INSR; HHF5; CD220; IR] |
| Gene, Accession # | [INSR], Gene ID: 3643, NCBI: P06213.4, UniProt: P06213 |
| Catalog # | MBS125832 |
| Price | $235, $350, $525 |
| Order / More Info | Phospho-Insulin Receptor beta-Y1189 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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