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Antigenic Specificity | Rab5 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. |
Immunogen | Immunogen: A synthesized peptide derived from human Rab5. Subcellular Localization: Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Cytoplasmic vesicle. Cell projection, ruffle. Membrane. Cytoplasm, cytosol. Enriched in stage I melanosomes. Alternates between membrane-bound and cytosolic forms. |
Other Names | [Ras-related protein Rab-5A; RAB5A; RAB5], [RAB5A; RAB5A; RAB5; RAB5] |
Gene, Accession # | [RAB5A], Gene ID: 5868, NCBI: NP_001278977.1, UniProt: P20339 |
Catalog # | MBS179758 |
Price | $160, $340, $340 |
Order / More Info | Rab5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |