Human CD41 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD41
Clone[4AHIP8]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatbiotin conjugate
Size50 tests, 100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Block
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Description4AHIP8 reacts with a calcium-dependent complex of CD41/CD61 (GPIIb/IIIa), 135/120 kDa, expressed on normal platelets and megakaryocytes. CD41 antigen acts as a receptor for fibrinogen, von Willebrand factor (vWf), fibrinectin and vitronectin and mediates platelet adhesion and aggregation. GM1CD41 antibody completely inhibits ADP, epinephrine and collagen-induced platelet activation and partially inhibits restocetin and thrombin-induced platelet activation. It is useful in the morphological and physiological studies of platelets and megakaryocytes.* Application: Diagnosis of Glanzmann's Thrombasthenia and megakaryoblastic leukemias, deletion of alloantibodies, and anti-thrombotic therapy.
Immunogenn/a
Other Names[cd41 antigen; Cd41 antigen; Cd41 antigen]
Gene, Accession #[CD41], NCBI: BAS21495.2
Catalog #MBS8510504
Price$215, $280
Order / More InfoHuman CD41 Antibody from MYBIOSOURCE INC.
Product Specific References1. Knapp, W., et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York. 2. Feng R et al. (1998) Bone Marrow Transplant 12:121.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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