ZO 1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ZO 1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, porcinepredicted: guinea pig |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ZO 1 antibody detects endogenous levels of total ZO 1. Description: The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions.Function: TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton (PubMed:7798316, PubMed:9792688). The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epi |
| Immunogen | Immunogen: A synthesized peptide derived from human ZO 1 Subcellular Location: Cell Membrane. Cell Junction > Tight Junction. Movement of ZO-1 from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Tissue Specificity: The alpha-containing isoform is found in most epithelial cell junctions. The short isoform is found both in endothelial cells and the highly specialized epithelial junctions of renal glomeruli and Sertoli cells of the seminiferous tubules. < |
| Other Names | [Tight junction protein 1; Tight junction protein ZO-1; Tight junction protein ZO1; TJP1; Zo1; ZO1_HUMAN; Zona occludens 1; Zona occludens 1 protein; Zona occludens protein 1; Zonula occludens 1 protein; Zonula occludens protein 1] |
| Gene, Accession # | [ZO-1], Gene ID: 7082, NCBI: NP_003248.3, UniProt: Q07157 |
| Catalog # | MBS9601318 |
| Price | $240, $280 |
| Order / More Info | ZO 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Hui-Fang Wang, Jing-XueMa, Qing-LiShang, Jian-BinAn, Hai-TingChen; Journal: EUR J PHARMACOL. Crocetin inhibits the proliferation, migration and TGF-beta 2-induced epithelial-mesenchymal transition of retinal pigment epithelial cells. Wang J, Lu J, Xie X, Xiong J, Huang N, Wei H, Jiang S, Peng J; Journal: Int Immunopharmacol. Blend of organic acids and medium chain fatty acids prevents the inflammatory response and intestinal barrier dysfunction in mice challenged with enterohemorrhagic Escherichia coli O157:H7. Zou Y, Xiang Q, Wang J, Peng J, Wei H; Journal: Biomed Res Int. Oregano Essential Oil Improves Intestinal Morphology and Expression of Tight Junction Proteins Associated with Modulation of Selected Intestinal Bacteria and Immune Status in a Pig Model. |
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MYBIOSOURCE INC.
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