PLC gamma1 (Phospho Tyr783) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPLC gamma1 (Phospho Tyr783)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, monkey
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: Phospho-PLC gamma1 (Y783) Polyclonal Antibody detects endogenous levels of PLC gamma1 protein only when phosphorylated at Y783. Phospholipase C gamma 1 encoded by PLCG1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, phospholipase C gamma 1 causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, phospholipase C gamma 1 has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast gr
ImmunogenImmunogen: Synthesized peptide derived from human PLC gamma1 around the phosphorylation site of Y783
Other Names[Rabbit PLC gamma1 (phospho Tyr783); PLC1; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase gamma-1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1]
Gene, Accession #[PLCG1], Gene ID: 5335, NCBI: NP_002651.2, UniProt: P19174
Catalog #MBS9701147
Price$130, $220, $325
Order / More InfoPLC gamma1 (Phospho Tyr783) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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