IL-1 beta Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IL-1 beta |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.1 mg, 0.2 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), IHC (Immunohistochemistry), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monocytes are the main source of secreted IL1. They express predominantly IL1- beta while human keratinocytes express large amounts of IL1-alpha. Murine macrophages display a transition from IL1-beta to IL1-alpha production during maturation of monocytes into inflammatory macrophages.There are two functionally almost equivalent forms of IL1, IL1-alpha and IL1-beta that are encoded by two different genes. IL1-beta is the predominant form in humans while it is IL1-alpha in mice. Both forms of IL1 bind to the same receptor and therefore also show similar if not identical biological activities. The IL1-beta but not the IL1-alpha precursor must be processed before it can bind to the receptor. Both forms of IL1 bind to the same receptor and there |
| Immunogen | Source Note: Polyclonal anti IL-1b was produced from sera of rabbits immunized with synthetic protein containing Interleukin-1 beta antigenic determinants. Presentation: Lyophilized from 0.2um filtered solution in PBS pH 7.4. |
| Other Names | [Rabbit IL-1 beta purified; interleukin-1; hbgf; heparin binding; il1b; il-1 beta; il1-beta;; pab], [IL1B; IL1F2; IL-1 beta] |
| Gene, Accession # | [IL-1], Gene ID: 3553, NCBI: NP_000567.1, UniProt: P01584 |
| Catalog # | MBS551056 |
| Price | $280, $385 |
| Order / More Info | IL-1 beta Antibody from MYBIOSOURCE INC. |
| Product Specific References | • azithromycin and clarithromycin inhibit lipopolysaccharide-induced murine pulmonary neutrophilia mainly through effects on macrophage-derived granulocyte-macrophage colony-stimulating factor and interleukin-1β.J. Pharmacol. Exp. Ther., Oct 2009; 331: 104 - 113. • high sensitivity of β-cell replication to the inhibitory effects of interleukin-1β: modulation by adenoviral overexpression of igf2 in rat islets.J. Endocrinol., Oct 2009; 203: 55 - 63. • bacillus anthracis capsule activates caspase-1/ice and induces interleukin-1 release from differentiated thp-1 and human monocyte-derived dendritic cells.Infect. Immun., Sep 2009; 10.1128/IAI.00956-09. • Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling.Nephrol. Dial. Transplant., Sep 2009; 24: 2655 - 2665. • ccaat enhancer binding protein-β regulates matrix metalloproteinase-1 expression in interleukin-1β-stimulated a549 lung carcinoma cells.Mol. Cancer Res., Sep 2009; 7: 1517 - 1524. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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