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Antigenic Specificity | TFRC - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rabbit |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TFRC. It was validated on Western BlotTarget Description: TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
Immunogen | n/a |
Other Names | [transferrin receptor protein 1 isoform 1; Transferrin receptor protein 1; transferrin receptor protein 1; transferrin receptor; T9; p90] |
Gene, Accession # | [TFRC], Gene ID: 7037, NCBI: NP_003225, UniProt: P02786 |
Catalog # | MBS3216145 |
Price | $335 |
Order / More Info | TFRC - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |