Bax Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Bax antibody, protein, ELISA kits.
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| Antigenic Specificity | Bax |
| Clone | [E63] |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 5 Control Slides, 3 ml (Prediluted), 0.1 mL (Concentrate) |
| Concentration | n/a |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bax is a protein of the bcl-2 gene family. It promotes apoptosis by competing with bcl-2 proper. The Bax gene contains a small promoter element that complements a binding domain on the multi-faceted p53 tumor suppressor. Wild-type p53 has been demonstrated to upregulate the transcription of a chimeric reporter plasmid, utilizing the consensus promoter sequence of Bax approx. 50-fold over mutant p53. Mutations in this consensus sequence eliminate transcription of the reporter gene. Thus, it is likely that p53 promotes Bax's apoptotic faculties in vivo as a primary transcription factor. Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells. Bax targets mitochondrial mem-branes, inducing mitochondrial damage and cell death i |
| Immunogen | Immunogen: Synthetic peptide within Human Bax aa 1-100 (N-terminal). Reactivity Note: Paraffin, Frozen |
| Other Names | [Bax RMab], [Bax; Bax] |
| Gene, Accession # | [Bax], Gene ID: 24887, UniProt: Q63690 |
| Catalog # | MBS370130 |
| Price | $130, $215, $230 |
| Order / More Info | Bax Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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