PhosphoIRF3S386 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PhosphoIRF3S386 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Interferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFNinducible gene expression in response to viral infection (1). IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3gamma/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-7, and IRF-8/ ICSBP. All IRF proteins share homology in their aminoterminal DNAbinding domains. IRF family members regulate transcription through interactions with proteins that share similar DNAbinding motifs, such as IFNstimulated response elements (ISRE), IFN consensus sequence |
| Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Serine 386 of human IRF3 |
| Other Names | [IRF3; IRF3 Phospho (pS386); IRF3; Interferon regulatory factor 3;], [IRF3; IRF3; IRF-3] |
| Gene, Accession # | Gene ID: 3661, NCBI: NP_001184051.1, UniProt: Q14653 |
| Catalog # | MBS126200 |
| Price | $275, $430, $655 |
| Order / More Info | PhosphoIRF3S386 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Taniguchi, T. et al. (2001) Annu Rev Immunol 19, 623-55. 2. Honda, K. and Taniguchi, T. (2006) Nat Rev Immunol 6, 644-58. 3. Hiscott, J. et al. (1999) J. Interferon Cytokine Res. 19, 1-13. 4. Kim, T.Y. et al. (2003) J. Biol. Chem. 278, 15272-15278. 5. Yoneyama, M. et al. (2002) J. Interferon Cytokine Res. 22, 73-76. 6. Fitzgerald, K.A. et al. (2003) Nat. Immunol. 4, 491-496. 7. Kopp, E. and Medzhitov, R. (2003) Curr. Opin. Immunol. 15, 396-401. 8. Servant, M.J. et al. (2003) J. Biol. Chem. 278, 9441-9447. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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