Signal transducer and activator of transcription 3, STAT3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySignal transducer and activator of transcription 3, STAT3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC)
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DescriptionSTAT3 (Signal transducer and activator of transcription 3) is a transcription factor which in humans is encoded by the STAT3 gene.1 The protein encoded by this gene is a member of the STAT protein family. STATs are latent transcription factors that mediate cytokine- and growth factor-directed transcription. In many human cancers and transformed cell lines, Stat3 is persistently activated, and in cell culture, active Stat3 is either required for transformation, enhances transformation, or blocks apoptosis.2
ImmunogenImmunogen: A synthetic peptide (conjugated with KLH) corresponding to the N-terminal of mouse STAT3.
Other Names[Signal transducer and activator of transcription 3; STAT3], [STAT3; STAT3; APRF; HIES; APRF]
Gene, Accession #[STAT3], Gene ID: 6774, NCBI: NP_644805.1, UniProt: P40763
Catalog #MBS355121
Price$275
Order / More InfoSignal transducer and activator of transcription 3, STAT3 Antibody from MYBIOSOURCE INC.
Product Specific References1. Akira S, Nishio Y, Inoue M, Wang XJ, Wei S, Matsusaka T, Yoshida K, Sudo T, Naruto M, Kishimoto T (April 1994). Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 77 (1): 63-71. 2. Bromberg, J. F., Wrzeszczynska, M. H., Devgan, G., Zhao, Y., Pestell, R. G., Albanese, C., Darnell, J. E., Jr. Stat3 as an oncogene. Cell 98: 295-303, 1999.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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