GSK-3Beta Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-GSK-3Beta antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | GSK-3Beta |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, bovine |
| Isotype | n/a |
| Format | ATTO 488 conjugate |
| Size | 0.1 mg |
| Concentration | 1.3mg/mL |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects ~47kDa. Scientific Background: Glycogen synthase kinase 3, is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues. It has also been shown to regulate immune and migratory processes, and is tied to pathways of cell proliferation and apoptosis (1-3). In mammals, it is encoded by two genes- GSK-3Alpha and GSK-3Beta. They are structurally similar, but functionally non-identical. GSK-3Alpha is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3Beta negatively regulates cardiac hypertrophy and cardiac development through its effect on WNT signaling (4). GSK-3 alpha and GSK-3 beta share 85% amino acid identity. GSK-3 has been impl |
| Immunogen | n/a |
| Other Names | [Glycogen Synthase kinase 3 beta; GSK 3 beta; GSK 3B; GSK-3 beta; GSK3B; GSK3B_Human; GSK3beta isoform], [GSK3B; GSK3B; GSK-3 beta] |
| Gene, Accession # | Gene ID: 2932, NCBI: NP_001139628.1, UniProt: P49841 |
| Catalog # | MBS805014 |
| Price | $390 |
| Order / More Info | GSK-3Beta Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Jope R.S. (2007) Neurochem Res. 32(4-5): 577-595. 2. Wang H. (2011) Cytokind. 53(2): 130-140. 3. Mills C.N. (2011) Front Mol Neurosci. 47(4): 47. 4. Hardt S.E., Sadoshima J. (2002) Circ Res. 90(10): 1055-1063. 5. Doble D.W., Woodgett J.R. (2003) J Cell Sci. 116(Pt7): 1175-1186. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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