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Antigenic Specificity | ovine CD34 |
Clone | [EQ-8D11-C1] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2a |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), CELISA, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: anti-ovine CD34. Purified monoclonal mouse antibody. Background: CD34 is a type I membrane protein with an apparent MW of approximately 115 kDa. It is aputative adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. CD34 is expressed specifically on immature normal human marrow cells, including hematopoietic progenitor cells (2). It is thought to act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. |
Immunogen | Immunogen: genetic immunisation with cDNA encoding the extracellular domain of ovineCD34. Selection: based on recognition of the complete native protein expressed on transfectedmammalian cells |
Other Names | [CD34; hematopoietic progenitor cell antigen CD34; CD34 antigen; CD34 molecule; CD34], [CD34; CD34] |
Gene, Accession # | Gene ID: 281051, NCBI: BAA78476.1 |
Catalog # | MBS468013 |
Price | $505 |
Order / More Info | ovine CD34 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shaw, SWS et al 2011: Sheep amniotic fluid derived CD34 stem cells could engraft and restorethe hematopoietic system of NSG mice. ISSCR 9th annual meeting, Poster board #2416Porada CD et al (2008): Development and characterization of a novel CD34 monoclonal antibodythat identifies sheep hematopoietic stem/progenitor cells. Exp Hematol, 36/12: 1739-1749.Civin CI et al (1984): Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cellsurface antigen defined by a monoclonal antibody raised against KG-1a cells. J Immunol. 133/1:157-65. |