SETD2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySETD2
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: SETD2 Antibody detects endogenous levels of total SETD2. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
ImmunogenImmunogen: Recombinant protein of human SETD2
Other Names[HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP]
Gene, Accession #[SETD2], Gene ID: 29072, NCBI: NP_054878.5, UniProt: Q9BYW2
Catalog #MBS8516680
Price$290
Order / More InfoSETD2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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