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Antigenic Specificity | TTBK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TTBK2 antibody detects endogenous levels of total TTBK2. Function: Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro.Subunit Structure: Interacts with CEP164.Similarity: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoskeleton; Cytosol; Nucleus |
Other Names | [KIAA0847; mKIAA0847; SCA11; Spinocerebellar ataxia 11; Tau tubulin kinase 2; Tau-tubulin kinase 2; TTBK; TTBK 2; TTBK1; TTBK2; TTBK2_HUMAN; TTK] |
Gene, Accession # | [TTBK2], Gene ID: 146057, NCBI: NP_775771.3, UniProt: Q6IQ55 |
Catalog # | MBS9604202 |
Price | $240, $280 |
Order / More Info | TTBK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |