KPNA4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKPNA4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionKPNA4 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. Molecules containing the classical nuclear localization signal (NLS) are transported into the nucleus by alpha/beta heterodimers. KPNA3 has been shown to be important in the TNF-α-induced nuclear import of NF-κB. It is also involved in the stress-mediated nuclear stabilization of p53 and the nuclear import and replication of HIV-1 in
ImmunogenImmunogen: KPNA4 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA4. Buffer: KPNA4 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[KPNA4; QIP1; SRP3; IPOA3; QIP1; Importin subunit alpha-3; Importin alpha Q1; Qip1; karyopherin alpha 4 (importin alpha 3)], [KPNA4; KPNA4; QIP1; SRP3; IPOA3; QIP1; Qip1]
Gene, Accession #[KPNA4], Gene ID: 3840, NCBI: EAW78632, UniProt: O00629
Catalog #MBS151257
Price$375
Order / More InfoKPNA4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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