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Antigenic Specificity | c-Jun |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins, and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activate c-Jun. |
Immunogen | Immunogen: E. coli-expressed recombinant human c-Jun fusion protein. Positive Control: Recombinant human c-Jun |
Other Names | [JUN; AP1; p39; c-Jun], [JUN; JUN; AP1; AP-1; c-Jun; AP1] |
Gene, Accession # | [c-Jun], Gene ID: 3725, NCBI: NP_002219.1, UniProt: P05412 |
Catalog # | MBS840826 |
Price | $150, $290 |
Order / More Info | c-Jun Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |