Phospho-GSK3 beta (Ser9) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-GSK3 beta (Ser9) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunoflurescene (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-GSK3 beta (Ser9) antibody detects endogenous levels of GSK3 beta only when phosphorylated at Serine 9. Description: GSK3B a proline-directed protein kinase of the GSK family. Phosphorylates and inactivates glycogen synthase. Participates in the Wnt signaling pathway. Involved in energy metabolism, neuronal cell development, and body pattern formation.Function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires |
| Immunogen | Immunogen: A synthesized peptide derived from human GSK3 beta around the phosphorylation site of Serine 9 Subcellular Location: Cytoplasm. Nucleus. Cell Membrane. The phosphorylated form shows localization to cytoplasm and cell membrane. The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosophorylated form to the cell membrane. Tissue Specificity: Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and T |
| Other Names | [Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3B; GSK3B_HUMAN; GSK3beta isoform; Serine/threonine-protein kinase GSK3B] |
| Gene, Accession # | [GSK3B], Gene ID: 2932, NCBI: NP_001139628.1, UniProt: P49841 |
| Catalog # | MBS9600628 |
| Price | $240, $280 |
| Order / More Info | Phospho-GSK3 beta (Ser9) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhang YM, Zhang YY, Bulbul A, Shan X, Wang XQ, Yan Q; Journal: FEBS Lett. Baicalin promotes embryo adhesion and implantation by upregulating fucosyltransferase IV (FUT4) via Wnt/beta-catenin signaling pathway. Zheng Q, Zhang D, Yang YU, Cui X, Sun J, Liang C, Qin H, Yang X, Liu S, Yan Q; Journal: Cell Death Differ. MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and a1, 3-fucosylation. Zhang P, Song Y, Sun Y, Li X, Chen L, Yang L, Xing Y; Journal: FASEB J. AMPK/GSK3beta/beta-catenin cascade-triggered overexpression of CEMIP promotes migration and invasion in anoikis-resistant prostate cancer cells by enhancing metabolic reprogramming. Wei A, Fan B, Zhao Y, Zhang H, Wang L, Yu X, Yuan Q, Yang D, Wang S; Journal: Oncotarget. ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3beta/beta-catenin signaling pathway. Liu Y, Geng L, Zhang J, Wang J, Zhang Q, Duan D, Zhang Q; Journal: Mar Drugs. Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway. |
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MYBIOSOURCE INC.
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