VDAC1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-VDAC1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | VDAC1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria (1). In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics (2). Homodimerization of VDAC may be a mechanism for changing mitochondrial permeability and supporting release of cytochrome c (3). In mammalian cells, there are three VDAC isoforms, VDAC1, which is the most widely expressed isoform, as well as VDAC2 and VDAC3 (4, 5). |
| Immunogen | Immunogen: Recombinant protein of human VDAC1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [VDAC1; MGC111064; PORIN; PORIN-31-HL] |
| Gene, Accession # | [VDAC1], Gene ID: 7416, NCBI: NP_003365.1, UniProt: P21796 |
| Catalog # | MBS8503941 |
| Price | $310 |
| Order / More Info | VDAC1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hodge, T. and Colombini, M. (1997) J Membr Biol 157, 271-9. 2. Shimizu, S. et al. (1999) Nature 399, 483-7. 3. Zheng, Y. et al. (2004) Oncogene 23, 1239-47. 4. Craigen, W.J. and Graham, B.H. (2008) J Bioenerg Biomembr 40, 207-12. 5. Yamamoto, T. et al. (2006) J Proteome Res 5, 3336-44. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies