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Antigenic Specificity | RAB5A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rab5 is a member of the Ras superfamily of small Rab GTPases. Rab5 is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis (1). The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis (1,2). Rab5 exerts its function by interacting with several Rab5-specific effectors (1-3). These proteins form complexes with Rab5 on a specialized Rab domain of the endosome and promote recycling of Rab5-cargo targets between endosome and the plasma membrane. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [RAB5A; RAB5], [RAB5A; RAB5A; RAB5; RAB5] |
Gene, Accession # | [RAB5A], Gene ID: 5868, NCBI: P20339.2, UniProt: P20339 |
Catalog # | MBS127357 |
Price | $200, $275, $430 |
Order / More Info | RAB5A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |