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Antigenic Specificity | Human STAT3 |
Clone | [7G3H4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human STAT3. STAT3 is a key signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development. STAT3 is also constitutively activated in a number of human tumors, possesses oncogenic potential, and anti-apoptotic activities. Following phosphorylation at Y705, STAT3 dimerizes, translocates to the nucleus and binds DNA. Transcriptional activation seems to be regulated by phosphorylation at Ser 727. |
Immunogen | Immunogen Description: Purified recombinant fragment of STAT3 expressed in E Coli. |
Other Names | [STAT3 (clone 7G3H4) IHC-plus; STAT3; Acute-phase response factor; APRF; DNA-binding protein APRF; HIES; Human STAT3], [STAT3; STAT3; APRF; HIES; ADMIO; APRF] |
Gene, Accession # | [STAT3], Gene ID: 6774, NCBI: NP_003141.2, UniProt: P40763 |
Catalog # | MBS246112 |
Price | $530 |
Order / More Info | Human STAT3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |