CD253 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD253
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total CD253 protein. Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.Wiley S.R., Immunity 3:673-682(1995).Pitti R.M., J. Biol. Chem. 271:12687-12690(1996).Hymowitz S.G., Mol. Cell 4:563-571(1999).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CD253.
Other Names[Tumor necrosis factor ligand superfamily member 10; TNF-related apoptosis-inducing ligand; Protein TRAIL; Apo-2 ligand; Apo-2L]
Gene, Accession #[CD253], Gene ID: 8743, NCBI: NP_001177871.1, UniProt: P50591
Catalog #MBS9412933
Price$200, $255
Order / More InfoCD253 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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