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Antigenic Specificity | CD253 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CD253 protein. Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.Wiley S.R., Immunity 3:673-682(1995).Pitti R.M., J. Biol. Chem. 271:12687-12690(1996).Hymowitz S.G., Mol. Cell 4:563-571(1999). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CD253. |
Other Names | [Tumor necrosis factor ligand superfamily member 10; TNF-related apoptosis-inducing ligand; Protein TRAIL; Apo-2 ligand; Apo-2L] |
Gene, Accession # | [CD253], Gene ID: 8743, NCBI: NP_001177871.1, UniProt: P50591 |
Catalog # | MBS9412933 |
Price | $200, $255 |
Order / More Info | CD253 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |