N-WASP Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | N-WASP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human N-WASP. Wiskott-Aldrich syndrome proteins (WASPs) mediate actin dynamics by activating the Arp2/3 actin nucleation complex in response to activated Rho family GTPases. In mammals, five WASP family members have been described. Hematopoietic WASP and ubiquitously expressed N-WASP are autoinhibited in unstimulated cells. Upon stimulation they are activated by cdc42, which relieves the autoinhibition in conjunction with phosphatidyl inositol 4,5-bisphosphate. Three WAVE (Wasf, SCAR) family proteins are similar in sequence to WASP and N-WASP but lack the WASP/N-WASP autoinhibition domains and are indirectly activated by Rac (reviewed in 1). Both WASP and WAVE functions appear to be essential, as knockout of either N-WA |
| Immunogen | Immunogen: A Fusion protein of human N-WASP |
| Other Names | [WASL; N-WASP; N-WASP; WASL; DKFZp779G0847; MGC48327; N-WASP; NWASP], [WASL; WASL; NWASP; N-WASP; N-WASP] |
| Gene, Accession # | Gene ID: 8976, NCBI: NP_003932.3, UniProt: O00401 |
| Catalog # | MBS125982 |
| Price | $275, $430 |
| Order / More Info | N-WASP Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Millard, T.H. et al. (2004) Biochem J. 380, 1-17. 2. Yan, C. et al. (2003) EMBO J. 22, 3602-3612. 3. Snapper, S.B. et al. (2001) Nat. Cell Biol. 3, 897-904. 4. Zhang, J. et al. (1999) J. Exp. Med. 190, 1329-4132. 5. Suetsugu, S. et al. (1999) Biochem. Biophys. Res. Commun. 260, 296-302. 6. Sossey-Alaoui, K. et al. (2002) Oncogene 21, 5967-5974. 7. Sossey-Alaoui, K. et al. (2005) Exp. Cell Res. 308, 135-145. 8. Sossey-Alaoui, K. et al. (2007) Am J Pathol 170, 2112-21. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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