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Antigenic Specificity | BCL2L1 (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat (predicted reactivity: mouse, porcine) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This BCL2L1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 195-229 amino acids from the C-terminal region of human BCL2L1. Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(S) promotes apoptosis. |
Immunogen | n/a |
Other Names | [Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X; BCL2L1; BCL2L; BCLX] |
Gene, Accession # | [BCL2L1], Gene ID: 598, NCBI: NP_001182.1, UniProt: Q07817 |
Catalog # | MBS9214218 |
Price | $165, $370 |
Order / More Info | BCL2L1 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Boise L.H.,et al.Cell 74:597-608(1993). Ban J.,et al.Biochem. Biophys. Res. Commun. 248:147-152(1998). Inohara N.,et al.Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases. Bechtel S.,et al.BMC Genomics 8:399-399(2007). Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. |