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Antigenic Specificity | KPNA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KPNA4 antibody detects endogenous levels of total KPNA4. Description: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.Function: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS |
Immunogen | Immunogen: A synthesized peptide derived from human KPNA4 Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Highly expressed in testis, ovary, small intestine, heart, skeletal muscle, lung and pancreas, but barely detectable in kidney, thymus, colon and peripheral blood leukocytes. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (90%), Xenopus (90 |
Other Names | [FLJ31113; IMA3_HUMAN; Importin alpha 3; Importin alpha 4 subunit; Importin alpha Q1; Importin subunit alpha 3; Importin subunit alpha-3; IPO A3; IPOA 3; IPOA3; Karyopherin alpha 4 (importin alpha 3); Karyopherin alpha 4; Karyopherin alpha 4 importin alpha 3; Karyopherin alpha 4 subunit; Karyopherin subunit alpha 4; Karyopherin subunit alpha-4; KPNA 4; Kpna4; MGC12217; MGC26703; OTTHUMP00000213880; QIP 1; Qip1; Qip1 protein; SRP 3; SRP3] |
Gene, Accession # | [KPNA4], Gene ID: 3840, NCBI: NP_002259.1, UniProt: O00629 |
Catalog # | MBS9607416 |
Price | $240, $280 |
Order / More Info | KPNA4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |