Phospho-CHEK1-S280 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-CHEK1-S280
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding S280 of human CHEK1 Calculated Molecular Weight: 54kDa
Other Names[Phospho-CHEK1-S280: CHK1], [CHEK1; CHEK1; CHK1; CHK1]
Gene, Accession #[CHEK1], Gene ID: 1111, NCBI: O14757.2, UniProt: O14757
Catalog #MBS125258
Price$235, $350, $525
Order / More InfoPhospho-CHEK1-S280 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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