Edit |   |
---|---|
Antigenic Specificity | BCL2L1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total BCL2L1 protein. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have b |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human BCL2L1. |
Other Names | [BCL2L1; BCL-XL/S; BCL2L; BCLX; Bcl-X] |
Gene, Accession # | [BCL2L1], Gene ID: 598, NCBI: NP_001182.1, UniProt: Q07817 |
Catalog # | MBS9406115 |
Price | $255 |
Order / More Info | BCL2L1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |