Edit |   |
---|---|
Antigenic Specificity | VWF |
Clone | [907CT12.1.9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is generated from a mouse immunized with.VWF recombinant protein. Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. |
Immunogen | n/a |
Other Names | [von Willebrand factor; vWF; von Willebrand antigen 2; von Willebrand antigen II; VWF; F8VWF] |
Gene, Accession # | [VWF], Gene ID: 7450, NCBI: NP_000543.2, UniProt: P04275 |
Catalog # | MBS9200676 |
Price | $165, $370 |
Order / More Info | VWF Antibody from MYBIOSOURCE INC. |
Product Specific References | Bonthron D.,et al.Nucleic Acids Res. 14:7125-7128(1986). Mancuso D.J.,et al.J. Biol. Chem. 264:19514-19527(1989). Scherer S.E.,et al.Nature 440:346-351(2006). Verweij C.L.,et al.EMBO J. 5:1839-1847(1986). Verweij C.L.,et al.EMBO J. 5:3074-3074(1986). |