Human APEX1 / APE1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human APEX1 / APE1 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | Gibbon, chimpanzee, gorilla, human, orangutan. predicted reactivity: monkey, bat, horse, porcine (at least 90% immunogen sequence identity) |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 0.5 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human APEX1 / APE1. Reported variants represent identical protein (NP_001632.2; NP_542379.1; NP_542380.1). Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. |
| Immunogen | Immunogen Description: Synthetic peptide PKRGKKGAVAEDGD-C from the N-terminus of human APEX1 / APE1 (NP_001632.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%); Marmoset, Panda, Bat, Horse, Pig (93%); Rabbit (86%). |
| Other Names | [APEX1 / APE1 (N-Terminus) IHC-plus; APEX1; AP endonuclease class I; AP lyase; APE; APE-1; APEN; APE1; APEX nuclease; Redox factor-1; AP endonuclease 1; APEX; APX; Protein REF-1; REF-1; REF1; Human APEX1; APE1], [APE1] |
| Gene, Accession # | [APEX1], Gene ID: 328, NCBI: NP_001632.2, UniProt: P27695 |
| Catalog # | MBS247978 |
| Price | $530 |
| Order / More Info | Human APEX1 / APE1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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