Phospho-SMAD3 (S213) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-SMAD3 (S213) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: chicken, mouse, porcine, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.34 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SMAD3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S213 of human SMAD3. SMAD3, a receptor regulated SMAD (R-SMAD) is a transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinase. SMAD3 is estimated to account for at least 80% of all TGF-beta-mediated response. Activated type I receptor phosphorylates receptor-activated SMADS (RSMADS) at their c-terminal two extreme serines in the SSXS motif. The phosphorylated R-SMAD translocate into nucleus, where they regulate transcription of target genes. SMAD3 signal transduction appears to be important in the rgulation of muscle-specific genes. Loss |
| Immunogen | n/a |
| Other Names | [Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3; SMAD3; MADH3] |
| Gene, Accession # | [SMAD3], Gene ID: 4088, NCBI: NP_001138574.1, UniProt: P84022 |
| Catalog # | MBS9205130 |
| Price | $165, $370 |
| Order / More Info | Phospho-SMAD3 (S213) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Imoto, S., et al., FEBS Lett. 579(13):2853-2862 (2005). Dubrovska, A., et al., Oncogene 24(14):2289-2297 (2005). Furumatsu, T., et al., J. Biol. Chem. 280(9):8343-8350 (2005). Kobayashi, T., et al., Biochem. Biophys. Res. Commun. 327(2):393-398 (2005). Kamaraju, A.K., et al., J. Biol. Chem. 280(2):1024-1036 (2005). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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