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Antigenic Specificity | GAD67 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. |
Immunogen | Immunogen: GAD67 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 5 and 216 of GAD67 |
Other Names | [Affinity Purified Rabbit GAD67; GAD67; GAD67; GAD67; GAD1; FLJ45882; GAD-67; GAD-67; glutamate decarboxylase 1; glutamate decarboxylase 67 kDa isoform; GAD-67; GAD 67; GAD 67; SCP; GAD] |
Gene, Accession # | [GAD67], Gene ID: 2571 |
Catalog # | MBS5311832 |
Price | $485 |
Order / More Info | GAD67 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |