Mcl1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMcl1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, monkey
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration200 ug/ml
ApplicationsImmunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionMcl-1 is a 37 kDa Bcl-2-related protein with an apparent molecular weight of 43 kDa on SDS-PAGE. Mcl-1 was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-beta1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.
ImmunogenImmunogen: Mcl1 antibody was raised in Rabbit using synthetic peptide corresponding to residues surrounding amino acid 131 of human Mcl-1 as the immunogen.
Other Names[Rabbit Mcl1; Mcl1; Mcl1; MGC1839; Mcl-1; EAT; mcl1/EAT; Mcl1; MCL1S; MCL1L; MGC104264; Mcl-1; TM; Mcl 1; Mcl 1]
Gene, Accession #[Mcl1]
Catalog #MBS5311134
Price$430
Order / More InfoMcl1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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