Human BACE1 / BACE Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human BACE1 / BACE |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | Gibbon, gorilla, human, monkey, rat. predicted reactivity: mouse, bovine, hamster (at least 90% immunogen sequence identity) |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human BACE1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ZBTB47 (44%). Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. |
| Immunogen | Immunogen Description: Synthetic 18 amino acid peptide from near N-terminus of human BACE1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rat (100%); Mouse, Bovine, Hamster, Panda (94%); Bat (89%). |
| Other Names | [BACE1 / BACE (N-Terminus) IHC-plus; BACE1; APP beta-secretase; Asp 2; ASP2; Aspartyl protease 2; Aspartylprotease 2; Beta-secretase; Beta-site APP-cleaving enzyme; BACE; HSPC104; KIAA1149; B-Secretase; Beta-secretase 1; Memapsin-2; Human BACE1; BACE], [BACE] |
| Gene, Accession # | [BACE1], Gene ID: 23621, NCBI: NP_036236.1, UniProt: P56817 |
| Catalog # | MBS240146 |
| Price | $530 |
| Order / More Info | Human BACE1 / BACE Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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