Human Transcriptional enhancer factor TEF-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Transcriptional enhancer factor TEF-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription |
| Immunogen | Immunogen: Recombinant human Transcriptional enhancer factor TEF-1 protein(135-215aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23793 / sc-292514 / sc-134070 |
| Other Names | [NTEF-1; Protein GT-IIC; TEA domain family member 1; TEAD-1; Transcription factor 13; TCF-13; TEAD1; TCF13; TEF1], [TEAD1; TEAD1; AA; REF1; TCF13; TEF-1; NTEF-1; TCF-13; TEAD-1; TCF13; TEF1; TEAD-1; TCF-13] |
| Gene, Accession # | [TEAD1], Gene ID: 7003, NCBI: NP_068780.2, UniProt: P28347 |
| Catalog # | MBS1491680 |
| Price | $120, $160 |
| Order / More Info | Human Transcriptional enhancer factor TEF-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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