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Antigenic Specificity | NCBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NCBP1 protein. Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human NCBP1. |
Other Names | [CBP80; MGC2087; NCBP; nuclear cap binding protein subunit 1; 80kDa] |
Gene, Accession # | [NCBP1], Gene ID: 4686, NCBI: NP_002477.1, UniProt: Q09161 |
Catalog # | MBS9407569 |
Price | $200, $255 |
Order / More Info | NCBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |