CHOP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCHOP
Clone2B1
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: CHOP protein detects endogenous levels of DDIT3. DDIT3 (DNA damage inducible transcript 3) encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of DDIT3 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding
ImmunogenImmunogen: Synthetic Peptide of CHOP at AA range of 10-90
Other Names[Mouse CHOP Mouse (2B1); DDIT3]
Gene, Accession #[CHOP], Gene ID: 1649, NCBI: NP_001181986.1, UniProt: P35638
Catalog #MBS9700546
Price$130, $220, $325
Order / More InfoCHOP Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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