rat capsaicin receptor (819-838) Antibody from MYBIOSOURCE INC.

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Antigenic Specificityrat capsaicin receptor (819-838)
Clonemonoclonal
Host SpeciesMouse
Reactive Speciesmouse, rat
IsotypeIgG
FormatProtein G purified
Size0.05 mL
Concentration1ug/ul
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: A high level of specificity has been confirmed by WB and immunohistochemical staining of rat DRG. The capsaicin receptor is involved in the detection of noxious chemical and thermal stimuli. It seems to mediate proton influx and to be involved in intracellular acidosis in nociceptive neurons. It may also mediate inflammatory pain and hyperalgesia. It is activated by vanilloids, such as capsaicin, and temperatures higher than 42' degree C. The capsaicin receptor is probably as homotetramer but may also form a heteromeric channel with TRPV3. It interacts with calmodulin, PRKCM and CSK and with PRKCG and NTRK1. There are 3 named isoforms produced by alternative splicing. The capsaicin receptor is a transmembrane protein that local
ImmunogenImmunogen: A synthetic peptide (C-GSLKPEDAEVFKDSMVPGEK) as a part of rat VR1 protein (aa: 819-838) conjugated to KLH has been used as the immunogen. Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide.
Other Names[capsaicin receptor; Transient receptor potential cation channel subfamily V member 1; transient receptor potential cation channel subfamily V member 1; transient receptor potential cation channel subfamily V member 1; Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1]
Gene, Accession #Gene ID: 7442, NCBI: AAG43466.1
Catalog #MBS4152676
Price$515
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Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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