CD31 (PECAM-1), Human Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CD31 (PECAM-1), Human |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 5 mL, 1 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Formalin/Paraffin, Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody JC70A primarily is used for the immunohistological detection of endothelial cells in Formalin-fixed tissues. Positive reactions are expected as well in normal as in transformed tissue. The antibody frequently is used for evaluation of angiogenesis in proliferating tumours (e.g. in mamma carcinoma, colorectal carcinoma and lung cancer). Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) or CD31 belongs to a group of transmembrane glycoproteins of the immunoglobulin super-family of adhesion molecules. It is exprimed predominantly by megakaryocytes, platelets, granulocytes, B-cell precursors and endothelial cells. It plays an important role in adhesion of leucocytes to blood vessel endothelia and for the cell migration throug |
| Immunogen | Immunogen: Spleen cell membrane preparation of hairy cell leukaemia affected patient |
| Other Names | n/a |
| Gene, Accession # | [CD31] |
| Catalog # | MBS397051 |
| Price | $360, $560 |
| Order / More Info | CD31 (PECAM-1), Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Parums D.V., Cordell J.L., Micklem K., Heryet A.R., Gatter K.C., and Mason D.Y. (1990) JC70: a new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections. J. Clin. Pathol. 43; 752-757. 2. Newman P.J., and Paddock C. (1995) CD31 cluster workshop report. In: Schlossman S.F. et al. Leucocyte Typing V. White Cell Differentiation Antigens. Oxford University Press, Oxford, N.Y., Tokyo pp 1259-1260. 3. Liao F., Huynh H.K., Eiora A., Greene T., Polizzi E., Muller W.A. (1995) Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM 1. J. Exp. Med. 182; 1337-1343. 4. Buckley C.D., Doyannas R., Newton J.P., Blystone S.D., Brown E.J., Watt S.M., et al. (1996) Identification of alpha v and beta 3 as a heterotypic ligand for CD31/PECAM-1. J. Cell Sci. 109; 437-445. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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