MYD88 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMYD88
Clone[AT22F11]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b,k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
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DescriptionMyeloid differentiation primary response gene 88 (MYD88) is adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes.
ImmunogenImmunogen: Recombinant human MYD88 (1-309aa) purified from E. coli
Other Names[Myeloid differentiation primary response protein MyD88; MYD88D], [MYD88; MYD88; MYD88D]
Gene, Accession #[MYD88], Gene ID: 4615, NCBI: NP_002459, UniProt: Q99836
Catalog #MBS200244
Price$240, $315
Order / More InfoMYD88 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBonnert TP, et al. (January 1997). FEBS Letters 402 (1): 81-4.; Lord KA, et al. (1990). Oncogene 5 (7): 1095-7.; Arancibia SA, et al. (2007). Biological research 40 (2): 97-112.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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