Bak Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Bak |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human Bak. Bak is a proapoptotic member of the Bcl-2 family (1). This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway (2,3). Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death (4,5). |
| Immunogen | Immunogen: A synthetic -peptide of human Bak |
| Other Names | [BAK1; BAK1; BAK; BAK-LIKE; BCL2L7; CDN1; MGC117255; MGC3887; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7;], [BAK1; BAK1; BAK; CDN1; BCL2L7; BAK-LIKE; BAK; BCL2L7; CDN1; Bcl2-L-7] |
| Gene, Accession # | Gene ID: 578, NCBI: NP_001179.1, UniProt: Q16611 |
| Catalog # | MBS125128 |
| Price | $200, $275, $430 |
| Order / More Info | Bak Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Gross, A. et al. (1999) Genes Dev. 13, 1899-1911. 2. Wei, M.C. et al. (2001) Science 292, 727-730. 3. Zong, W.X. et al. (2001) Genes Dev. 15, 1481-1486. 4. Degenhardt, K. et al. (2002) J. Biol. Chem. 277, 14127-14134. 5. Wei, M.C. et al. (2000) Genes Dev. 14, 2060-2071. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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