Phospho-eIF2 alpha (Ser51) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-eIF2 alpha (Ser51) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-eIF2 alpha (Ser51) antibody detects endogenous levels of eIF2 alpha only when phosphorylated at Serine 51. Description: EIF2A a translation initiation factor that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40s ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex.Function: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to |
| Immunogen | Immunogen: A synthesized peptide derived from human eIF2 alpha around the phosphorylation site of Serine 51 Subcellular Location: Cytoplasmic Granule. The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity). Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%) |
| Other Names | [EIF 2 alpha; EIF 2; EIF 2A; EIF 2alpha; eIF-2-alpha; eIF-2A; EIF-2alpha; EIF2 alpha; EIF2; EIF2A; EIF2S1; Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa; Eukaryotic translation initiation factor 2 subunit 1 alpha; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; IF2A_HUMAN] |
| Gene, Accession # | [EIF2S1], Gene ID: 1965, NCBI: NP_004085.1, UniProt: P05198 |
| Catalog # | MBS9600859 |
| Price | $240, $280 |
| Order / More Info | Phospho-eIF2 alpha (Ser51) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Liu Y, Shen HJ, Wang XQ, Liu HQ, Zheng LY, Luo JD; Journal: J Cell Biochem. EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes. Cai Y, Zheng Y, Gu J, Wang S, Wang N, Yang B, Zhang F, Wang D, Fu W, Wang Z; Journal: Cell Death Dis. Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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