SIK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySIK2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: SIK2 antibody is predicted to not cross-react with other SIK protein family members. Salt-inducible kinase 2 (SIK2), like its closely related homolog SIK1, belongs AMPK subfamily of the Ser/Thr protein kinase family and negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1 alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing C
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide near the center of human SIK2.
Other Names[Salt-inducible protein kinase 2, Serine, threonine-protein kinase SNF1-like kinase 2, SNF1LK2, QIK, LOH11CR1I]
Gene, Accession #[SIK2], Gene ID: 23235, NCBI: EAW67148
Catalog #MBS9408046
Price$320
Order / More InfoSIK2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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