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Antigenic Specificity | SIK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SIK2 antibody is predicted to not cross-react with other SIK protein family members. Salt-inducible kinase 2 (SIK2), like its closely related homolog SIK1, belongs AMPK subfamily of the Ser/Thr protein kinase family and negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1 alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing C |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide near the center of human SIK2. |
Other Names | [Salt-inducible protein kinase 2, Serine, threonine-protein kinase SNF1-like kinase 2, SNF1LK2, QIK, LOH11CR1I] |
Gene, Accession # | [SIK2], Gene ID: 23235, NCBI: EAW67148 |
Catalog # | MBS9408046 |
Price | $320 |
Order / More Info | SIK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |