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Antigenic Specificity | GluA1/GluR1 |
Clone | [S355-1] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~100 kDa. Does not cross-react with GluR2. Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3). |
Immunogen | Immunogen: Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 |
Other Names | [Mouse Rat GluA1/GluR1 Glutamate Receptor IgG1; GluA1/GluR1 : APC/Cy7; AMPA 1; AMPA selective glutamate receptor 1; Glutamate receptor 1; GluA1; GLUH 1; GluR K1; GluRK1; Glr-1; Glur-1; HIPA; Glur1; GluR-A; AI853806; 2900051M01Rik; GluRA; Glr1; MGC13325; GLUH1; GluA1; GLUR1; HBGR1; GLURA; gluR-; GluA1; Glutamate receptor ionotropic AMPA 1; Glutamate receptor ionotropic; Gria 1; HBGR1; OTTHUMP00000160643; OTTHUMP00000165781; OTTHUMP00000224241; OTTHUMP00000224242; OTTHUMP00000224243] |
Gene, Accession # | [GluA1/GluR1], Gene ID: 50592, NCBI: NP_113796.1, UniProt: P19490 |
Catalog # | MBS8003334 |
Price | $510 |
Order / More Info | GluA1/GluR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Potier M.C., Spillantini M.G., Carter N.P. (1992) DNA Seq. 2(4): 211-218. 2. Puckett, C., et al. (1991) Proc. Nat. Acad. Sci. USA 88(17): 7557-7561. 3. Gregor, P., et al. (1993) Proc. Nat. Acad. Sci. USA 90: 3053-3057. |