Phospho-RFA2 (Thr21) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-RFA2 (Thr21) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-RFA2 (Thr21) antibody detects endogenous levels of RFA2 only when phosphorylated at Threonine 21. Description: RFA2 is absolutely required for simian virus 40 DNA replication in vitro. It participates in a very early step in initiation. A single-stranded DNA-binding protein.Function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to |
| Immunogen | Immunogen: A synthesized peptide derived from human RFA2 around the phosphorylation site of Threonine 21 Subcellular Location: Nucleus. Nucleus > PML body. Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage. Tissue Specificity: Translationally up-regulated in response to DNA damage (at protein level). Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Sheep, Dog, Xenopus Similarity: Pig (100%), Zebrafish (88%), Bovine (10 |
| Other Names | [60S acidic ribosomal protein P1; AA409079; AI325195; AU020965; ik:tdsubc_2g1; M(2)21C; MGC137236; OTTHUMP00000004008; p32; p34; RCJMB04_6d17 replication protein A2, 32kDa; REPA2; Replication factor A protein 2; Replication protein A 32 kDa subunit; Replication protein A 32kDa subunit; Replication protein A 34 kDa subunit; Replication protein A; Replication Protein A2 (32kDa); Replication protein A2; Replication protein A2, 32kDa; RF-A protein 2; Rf-A2; RFA; RFA2_HUMAN; RP-A p32; RP-A p34; RP21C; RPA 2; RPA 32; RPA; Rpa2; RPA32; RPA34; RpLP1; RpP2; xx:tdsubc_2g1; zgc:109822] |
| Gene, Accession # | [RFA2], Gene ID: 6118, NCBI: NP_001273005.1, UniProt: P15927 |
| Catalog # | MBS9600954 |
| Price | $240, $280 |
| Order / More Info | Phospho-RFA2 (Thr21) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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