PARD3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PARD3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PARD3 antibody detects endogenous levels of total PARD3. Function: Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions (By similarity). Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474). Required for establishment of neuronal polarity and normal axon formati |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Endomembrane System. Cell Junction. Cell Junction > Tight Junction. Cell Membrane. Cytoplasm > Cell Cortex. Cytoplasm > Cytoskeleton. Localized along the cell-cell contact region. Colocalizes with PARD6A and PRKCI at epithelial tight junctions. Colocalizes with the cortical actin that overlays the meiotic spindle during metaphase I and metaphase II (By similarity). Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cel |
| Other Names | [agouti signaling protein; ASIP; Atypical PKC isotype specific interacting protein; Atypical PKC isotype-specific-interacting protein; Baz; bazooka; Coagulation factor II receptor-like 2; CTCL tumor antigen se2-5; F2rl2; PAR-3; par-3 family cell polarity regulator alpha; par-3 family cell polarity regulator; PAR3 alpha; par3; PAR3-alpha; PARD-3; Pard3; PARD3_HUMAN; PARD3A; Partitioning defective 3 homolog; Partitioning-defective 3 homolog; Partitioning-defective protein 3, C. elegans, homolog of; SE2-5L16; SE2-5LT1; SE2-5T2; Thrombin receptor-like 2] |
| Gene, Accession # | [PARD3], Gene ID: 56288, NCBI: NP_001171714.1, UniProt: Q8TEW0 |
| Catalog # | MBS9604829 |
| Price | $240, $280 |
| Order / More Info | PARD3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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