eIF2alpha (Phospho-Ser51) Antibody from MYBIOSOURCE INC.

Search, find, compare suppliers for anti-eIF2alpha (Phospho-Ser51) antibody, protein, ELISA kits.

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Antigenic SpecificityeIF2alpha (Phospho-Ser51)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous level of eIF2a only when phosphorylated at serine 51. Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 51 (E-L-S(p)-R-R) derived from Human eIF2a.
Other Names[eIF2a (Phospho-Ser51); Eukaryotic translation initiation factor 2 subunit alpha; EIF-2A]
Gene, Accession #[eIF2alpha], Gene ID: 1965, NCBI: NP_004085.1, UniProt: P05198
Catalog #MBS9407695
Price$200, $255
Order / More InfoeIF2alpha (Phospho-Ser51) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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