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Antigenic Specificity | TLR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR4 is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide. In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB. |
Immunogen | Immunogen: TLR4 antibody was raised in Rabbit using synthetic peptide corresponding to residues surrounding amino acids 819 of rat TLR4 as the immunogen. |
Other Names | [Rabbit TLR4; TLR4; TLR4; TLR4; TLR-4; TLR 4; Toll Like Receptor 4; TLR 4; TOLL; TLR-4] |
Gene, Accession # | [TLR4] |
Catalog # | MBS5311237 |
Price | $445 |
Order / More Info | TLR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |