MYD88 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMYD88
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionMYD88 Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP. Recently, MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-κB activation. MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor, which are members in the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL-1 and IL-18, and MyD88-deficient mice lack responses to bacterial product LPS that employs Toll-like receptors 2
ImmunogenImmunogen: MD88 antibody was raised against a 16 amino acid peptide near the center of human MD88. Buffer: MYD88 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[MYD88; Myeloid differentiation primary response 88; MYD88D; myeloid differentiation primary response gene (88)], [MYD88; MYD88D]
Gene, Accession #[MYD88], Gene ID: 4615, NCBI: AAB49967.1, UniProt: U70451
Catalog #MBS150754
Price$375
Order / More InfoMYD88 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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