OGG1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityOGG1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: OGG1 antibody detects endogenous levels of total OGG1. Description: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for th
ImmunogenImmunogen: A synthesized peptide derived from human OGG1 Subcellular Location: Mitochondrion; Nucleus and Nucleus > Nucleoplasm. Nucleus Speckle. Nucleus Matrix. Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Bovine, Sheep, Dog Similarity: Bovine (85%), Sheep (85%), Dog (91%)
Other Names[8 hydroxyguanine DNA glycosylase; 8 oxoguanine DNA glycosylase 1; 8 oxoguanine DNA glycosylase; AP lyase; DNA (apurinic or apyrimidinic site) lyase; DNA apurinic or apyrimidinic site lyase; DNA lyase; DNA-(apurinic or apyrimidinic site) lyase; HMMH; HOGG 1; HOGG1; MMH; MUTM; N glycosylase; Ogg 1; Ogg1; OGG1_HUMAN; OGH 1; OGH1]
Gene, Accession #[OGG1], Gene ID: 4968, NCBI: NP_002533.1, UniProt: O15527
Catalog #MBS9607058
Price$240, $280
Order / More InfoOGG1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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