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Antigenic Specificity | MAG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Myelin-associated glycoprotein(MAG) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: MAG(Myelin-associated glycoprotein),also known as SIGLEC4A, is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR. It is though to be involved in the process of myelination. MAG is a sialic acid-binding SIGLEC protein and is a functional ligand for the NOGO receptor.The MAG gene is mapped on 19q13.12. Cleavage of GPI-linked proteins from axons protects growth cones from MAG-induced collapse, and dominant-negative NgR eliminates MAG inhibition of neurite outgrowth. MAG-resistant embryonic neurons were rendered |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MAG (114-132aa KYYFRGDLGGYNQYTFSEH), identical to the related rat and mouse sequences. |
Other Names | [Myelin-associated glycoprotein; myelin associated glycoprotein; GMA; MAG; MAG_HUMAN; Myelin associated glycoprotein; Myelin-associated glycoprotein; S MAG; Siglec 4a; Siglec-4a; SIGLEC4A], [MAG; MAG; GMA; S-MAG; SIGLEC4A; SIGLEC-4A; GMA] |
Gene, Accession # | [MAG], Gene ID: 4099, NCBI: P20916.1, UniProt: P20916 |
Catalog # | MBS175221 |
Price | $315 |
Order / More Info | MAG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |