MAG Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAG
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionDescription: Rabbit IgG polyclonal antibody for Myelin-associated glycoprotein(MAG) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: MAG(Myelin-associated glycoprotein),also known as SIGLEC4A, is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR. It is though to be involved in the process of myelination. MAG is a sialic acid-binding SIGLEC protein and is a functional ligand for the NOGO receptor.The MAG gene is mapped on 19q13.12. Cleavage of GPI-linked proteins from axons protects growth cones from MAG-induced collapse, and dominant-negative NgR eliminates MAG inhibition of neurite outgrowth. MAG-resistant embryonic neurons were rendered
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MAG (114-132aa KYYFRGDLGGYNQYTFSEH), identical to the related rat and mouse sequences.
Other Names[Myelin-associated glycoprotein; myelin associated glycoprotein; GMA; MAG; MAG_HUMAN; Myelin associated glycoprotein; Myelin-associated glycoprotein; S MAG; Siglec 4a; Siglec-4a; SIGLEC4A], [MAG; MAG; GMA; S-MAG; SIGLEC4A; SIGLEC-4A; GMA]
Gene, Accession #[MAG], Gene ID: 4099, NCBI: P20916.1, UniProt: P20916
Catalog #MBS175221
Price$315
Order / More InfoMAG Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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