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Antigenic Specificity | ATF2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3' ) or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3' ). In the nucleus, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, proliferation and death. In the cytoplasm, interacts with and perturbs HK1-and VDAC1-containing complexes at the mitochondrial outer membrane, thereby impairing mitochondrial membrane potential, inducing mitochondrial leakage and promoting |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human ATF2 (NP 001871.2). |
Other Names | [HB16; CREB2; TREB7; CREB-2; CRE-BP1] |
Gene, Accession # | [ATF2], Gene ID: 1386, NCBI: NP_001243019.1, UniProt: P15336 |
Catalog # | MBS8544839 |
Price | $280 |
Order / More Info | ATF2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |